Intermolecular Hydroaminoalkylation of Alkynes
Kaper T., Fischer M., Thye H., Geik D., Schmidtmann M., Beckhaus R., Doye S.
Intermolecular hydroaminoalkylation reactions of alkynes with secondary amines, which selectively give access to allylic amines with E configuration of the alkene unit, are achieved in the presence of titanium catalysts. Successful reactions of symmetrically substituted diaryl- and dialkylalkynes as well as a terminal alkyne take place with N-benzylanilines, N-alkylanilines, and N-alkylbenzylamines.