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UK Biobank Imaging Extension Approved
Integrative Neuroimaging Research
1 October 2012
UK Biobank is an on-going prospective epidemiological study that has already collected genetics, blood, lifestyle information and other data from a cohort of 500,000 subjects, to be followed over coming decades. The "UK Biobank Imaging Extension", which aims to bring back 100,000 of the cohort for multimodal neuroimaging and cardiac MRI (amongst other measures), has just been given the go-ahead. This will be by far the largest neuro/cardiac imaging study carried out to date, and will add very rich phenotyping to the project.
New FMRI Technique Produces Quantitative Measurement of Cerebral Physiology
Integrative Neuroimaging
8 March 2012
FMRI has long been a useful research tool, providing indirect indications of relative change in brain activity when the subject is presented with different stimuli. It has rarely been used in diagnostics as it does not produce numerical data. Currently, positron emission tomography (PET) scans are used to provide quantitative measurements of blood flow and volume in the brain for use in diagnosis. However, PET is expensive, has poor spatial resolution and exposes the patient to ionising radiation.