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<jats:p>Benzodiazepine-resistant status epilepticus is an ongoing clinical challenge. Burman et al. show that longer seizure duration is a useful clinical indicator of benzodiazepine resistance, and that resistance is caused by changes in GABAA receptor-mediated synaptic transmission. The findings could help optimise current management protocols.</jats:p>

Original publication

DOI

10.1093/brain/awz283

Type

Journal article

Journal

Brain

Publisher

Oxford University Press (OUP)

Publication Date

01/11/2019

Volume

142

Pages

3482 - 3501