Circadian rhythms and cognition in schizophrenia.
Wulff K., Joyce E.
Cognitive impairment is a core feature of schizophrenia. Evidence in this Journal suggests that disrupted circadian synchronisation of sleep-wake phases may be one cause. Circadian synchronisation depends on the external input of light-dark cues and the integrity of central nervous system circadian oscillators; these may represent new interventional targets to improve cognition.