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To date, most perfusion magnetic resonance imaging (MRI) methods using arterial spin labeling (ASL) have employed slab-selective inversion pulses or continuous labeling within a plane in order to obtain maps derived from all major blood vessels entering the brain. However, there is great potential for gaining additional information on the territories perfused by the major vessels if individual feeding arteries could be tagged. This study demonstrates noninvasive arterial perfusion territory maps obtained using two-dimensional (2D) selective inversion pulses. This method is designated "selective ASL" (SASL). The SASL method was used to tag the major arteries below the circle of Willis. A combination of 2D selective tagging and multislice readout allows perfusion territories to be clearly visualized, with likely applications to cerebrovascular disease and stroke.

Original publication

DOI

10.1002/mrm.10475

Type

Journal article

Journal

Magn Reson Med

Publication Date

06/2003

Volume

49

Pages

1133 - 1142

Keywords

Brain, Brain Mapping, Carotid Arteries, Cerebrovascular Circulation, Collateral Circulation, Humans, Magnetic Resonance Imaging, Radiography