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This review considers the manner in which inflammation in the CNS contributes to, and protects against, neurodegeneration. A series of questions are posed, first about primarily inflammatory diseases and the causes of neurodegeneration that occurs in them, and then about neurodegenerative diseases and stroke and the role that inflammation plays there. Common themes as well as disease-specific differences are highlighted in this survey of the recent human disease and animal model literature.

Original publication

DOI

10.1016/j.jneuroim.2006.11.013

Type

Journal article

Journal

J Neuroimmunol

Publication Date

03/2007

Volume

184

Pages

4 - 16

Keywords

Animals, Central Nervous System Diseases, Disease Models, Animal, Humans, Inflammation, Neurodegenerative Diseases