Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Defensive behaviors, such as withdrawing your hand to avoid potentially harmful approaching objects, rely on rapid sensorimotor transformations between visual and motor coordinates. We examined the reference frame for coding visual information about objects approaching the hand during motor preparation. Subjects performed a simple visuomanual task while a task-irrelevant distractor ball rapidly approached a location either near to or far from their hand. After the distractor ball appearance, single pulses of transcranial magnetic stimulation were delivered over the subject's primary motor cortex, eliciting motor evoked potentials (MEPs) in their responding hand. MEP amplitude was reduced when the ball approached near the responding hand, both when the hand was on the left and the right of the midline. Strikingly, this suppression occurred very early, at 70-80 ms after ball appearance, and was not modified by visual fixation location. Furthermore, it was selective for approaching balls, since static visual distractors did not modulate MEP amplitude. Together with additional behavioral measurements, we provide converging evidence for automatic hand-centered coding of visual space in the human brain.

Original publication

DOI

10.1523/JNEUROSCI.2955-09.2009

Type

Journal article

Journal

J Neurosci

Publication Date

23/09/2009

Volume

29

Pages

11841 - 11851

Keywords

Adult, Electromyography, Evoked Potentials, Motor, Female, Fixation, Ocular, Hand, Humans, Male, Middle Aged, Motor Activity, Motor Cortex, Photic Stimulation, Psychomotor Performance, Pyramidal Tracts, Time Factors, Transcranial Magnetic Stimulation, Uncertainty, Video Recording, Visual Perception, Young Adult