Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Direction discrimination of a moving tactile stimulus requires intact dorsal columns and provides a sensitive clinical test of somatosensory dysfunction. Cortical mechanisms are poorly understood. We have applied tangential skin pulls to the right lower leg during functional magnetic resonance imaging. Healthy subjects judged the direction of the skin pulls (task experiment, n = 7) or received skin pulls passively (no task experiment, n = 8). Second somatosensory cortex (S2) was activated in the task as well as no task experiment, and there was no significant difference in cortical activation between the two experiments. Within S2 nearly all subjects had prominent activations in the caudal and superficial part, i.e., in the opercular parietal (OP) area 1. S1 was activated in only one of the subjects. Thus, S2 and especially OP 1 seems to be important for processing of lateral skin stretch stimulation. The finding suggests that a lesion of this area might cause a disturbance in tactile direction discrimination which should be relevant for clinical testing.

Original publication

DOI

10.1007/s00221-008-1454-1

Type

Journal article

Journal

Exp Brain Res

Publication Date

09/2008

Volume

190

Pages

117 - 124

Keywords

Adult, Afferent Pathways, Brain Mapping, Female, Humans, Leg, Magnetic Resonance Imaging, Male, Mechanoreceptors, Parietal Lobe, Physical Stimulation, Psychophysics, Skin, Skin Physiological Phenomena, Somatosensory Cortex, Stress, Mechanical, Touch