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Human brain imaging has identified structural changes in gray and white matter that occur with learning. However, ascribing imaging measures to underlying cellular and molecular events is challenging. Here we review human neuroimaging findings of structural plasticity and then discuss cellular and molecular level changes that could underlie observed imaging effects. Greater dialog between researchers in these different fields would help to facilitate cross-talk between cellular and systems level explanations of how learning sculpts brain structure. © 2012 Nature America, Inc. All rights reserved.

Original publication

DOI

10.1038/nn.3045

Type

Journal article

Journal

Nature Neuroscience

Publication Date

01/04/2012

Volume

15

Pages

528 - 536