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We report a young woman with the abrupt onset of infectious mononucleosis due to Epstein-Barr virus associated with a subsequent autoimmune form of diabetes mellitus and myasthenia gravis with anti-muscle-specific kinase (MuSK) antibodies. The simultaneous onset of these two autoimmune diseases preceded by a systemic viral illness supports a causal relationship between MuSK antibodies and myasthenia gravis and suggests the possibility of a viral trigger in some cases.

Original publication

DOI

10.1002/mus.20746

Type

Journal article

Journal

Muscle Nerve

Publication Date

08/2007

Volume

36

Pages

264 - 266

Keywords

Adult, Autoantibodies, Diabetes Mellitus, Female, Humans, Infectious Mononucleosis, Myasthenia Gravis, Receptor Protein-Tyrosine Kinases, Receptors, Cholinergic