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An Uhthoff-like phenomenon was recently observed in a patient with clinically definite MS who experienced transient dysphonia brought on by exertion and relieved by cooling. The patient's dysphonia was felt to be related to intermittent temperature-dependent conduction block associated with a demyelinating plaque in the region of the left nucleus ambiguus. We have termed the patient's intermittent dysphonia 'laryngeal Uhthoff's phenomenon'.

Original publication

DOI

10.1177/135245859500100305

Type

Journal article

Journal

Mult Scler

Publication Date

11/1995

Volume

1

Pages

163 - 164

Keywords

Body Temperature, Demyelinating Diseases, Exercise, Female, Humans, Laryngeal Diseases, Magnetic Resonance Imaging, Middle Aged, Multiple Sclerosis, Voice Disorders