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A 55-year-old female is presented with transient cerebellar mutism caused by a well-circumscribed left pontine infarction due to postoperative basilar perforator occlusion. Although conventional T2 imaging shows a well-demarcated lesion confined to the pontine region, diffusion tensor imaging shows an asymmetry in fractional anisotropy in the superior cerebellar peduncle. This supports the general hypothesis that cerebellar mutism is caused by functional disruption of the dentate-rubro-thalamic tract. Correlating postoperative anatomic changes to a heterogenic clinical syndrome remains challenging, however.

Original publication

DOI

10.1007/s12311-013-0473-z

Type

Journal article

Journal

Cerebellum

Publication Date

10/2013

Volume

12

Pages

617 - 622

Keywords

Anisotropy, Cerebellum, Diffusion Tensor Imaging, Female, Humans, Middle Aged, Mutism, Pons, Thalamus