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For the first time, there is a pathogenic hypothesis of schizophrenia based upon reasonable empirical data. The hypothesis is that schizophrenia is a disorder arising from aberrant brain development. The neurodevelopmental view of schizophrenia is supported by neuropathological, epidemiological and clinical findings. Here, the evidence in favour of the model is summarized, together with a consideration of its weaknesses.

Type

Journal article

Journal

Curr Opin Neurobiol

Publication Date

04/1997

Volume

7

Pages

285 - 289

Keywords

Brain, Humans, Schizophrenia