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Thirteen patients with acute posterior multifocal placoid pigment epitheliopathy (APMPPE) were followed up for a period of from 1 to 20 years (median 5 years 8 months). Five patients developed lesions in the previously unaffected fellow eye during the follow up period. In three patients the condition progressed during a prolonged period without interruption. Widespread severe choroidal atrophy was a late feature in a number of cases. In seven out of thirteen cases, visual acuity remained defective (6/18 or less) in one or both eyes. The prevailing opinion that that APMPPE is self limiting may be incorrect.


Journal article


Trans Ophthalmol Soc U K

Publication Date



103 ( Pt 5)


517 - 522


Acute Disease, Adolescent, Adult, Eye Diseases, Female, Fluorescein Angiography, Follow-Up Studies, Fundus Oculi, Humans, Male, Middle Aged, Pigment Epithelium of Eye, Prognosis