Vanhaesebrouck AE., Webster R., Maxwell S., Rodriguez Cruz PM., Cossins J., Wickens J., Liu W-W., Cetin H., Cheung J., Ramjattan H., Palace J., Beeson D.

The efficacy of anticholinesterase medication may diminish over time. Vanhaesebrouck et al. use an animal model of acetylcholine receptor deficiency syndrome to show that beta-2 adrenergic receptor agonists ameliorate the damage to neuromuscular junction structure caused by prolonged anticholinesterase medication, and thereby counteract the decline in efficacy.

β2-Adrenergic receptor agonists ameliorate the adverse effect of long-term pyridostigmine on neuromuscular junction structure

Vanhaesebrouck AE., Webster R., Maxwell S., Rodriguez Cruz PM., Cossins J., Wickens J., Liu W-W., Cetin H., Cheung J., Ramjattan H., Palace J., Beeson D.

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