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An analysis of the Kozak consensus in retinal genes and its relevance to gene therapy.

Journal article

McClements ME. et al, (2021), Mol Vis, 27, 233 - 242

CRISPR genome engineering for retinal diseases

Chapter

Kantor A. et al, (2021), Progress in Molecular Biology and Translational Science

Promoter Orientation within an AAV-CRISPR Vector Affects Cas9 Expression and Gene Editing Efficiency

Journal article

Fry LE. et al, (2020), The CRISPR Journal, 3, 276 - 283

Extraction of Guide RNA from a Transcript for Association with Deactivated Cas9

Conference paper

McClements ME. et al, (2020), MOLECULAR THERAPY, 28, 280 - 281

CRISPR Interference–Potential Application in Retinal Disease

Journal article

Peddle CF. et al, (2020), International Journal of Molecular Sciences, 21, 2329 - 2329

RNA Editing as a Therapeutic Approach for Retinal Gene Therapy Requiring Long Coding Sequences

Journal article

Fry LE. et al, (2020), International Journal of Molecular Sciences, 21, 777 - 777

Effect of single guide nucleotide mismatch in CRISPR/Cas9-mediated disruption of the human rhodopsin gene in vitro

Conference paper

Peddle C. et al, (2019), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 60

Guide RNA orientation influences Cas9 expression in a single vector approach to CRISPR editing in a model system

Conference paper

Fry L. et al, (2019), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 60

Validation of Staphylococcus aureus Cas9 gRNAs targeting EGFP present in the rod cells of the Nrl-EGFP mouse line

Conference paper

Peddle C. et al, (2018), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 59

The Application of CRISPR/Cas9 for the Treatment of Retinal Diseases.

Journal article

Peddle CF. and MacLaren RE., (2017), Yale J Biol Med, 90, 533 - 541

Evaluation of the efficiency and specificity of short variants of the human PDE6b promoter in photoreceptor-like cells in vitro and ex vivo

Conference paper

Peddle CF. et al, (2017), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 58