Detailed Analysis of ITPR1 Missense Variants Guides Diagnostics and Therapeutic Design.
Journal article
Tolonen JP. et al, (2023), Mov Disord
Modulation and Regulation of Canonical Transient Receptor Potential 3 (TRPC3) Channels.
Journal article
Cole BA. and Becker EBE., (2023), Cells, 12
PTCH1mutant human cerebellar organoids are associated with altered neural development and early pathways of medulloblastoma oncogenesis
Preprint
van Essen MJ. et al, (2023)
Moonwalker Mouse
Chapter
Ibrahim MF. and Becker EBE., (2023), Essentials of Cerebellum and Cerebellar Disorders, 441 - 447
Purkinje Cell Patterning-Insights from Single-Cell Sequencing.
Journal article
Apsley EJ. and Becker EBE., (2022), Cells, 11
Cerebellar Modelling Using Human Induced Pluripotent Stem Cells
Chapter
van Essen MJ. et al, (2022), Neuromethods, 177, 1 - 21
High-resolution transcriptional landscape of xeno-free human induced pluripotent stem cell-derived cerebellar organoids
Journal article
Nayler S. et al, (2021), Scientific Reports, 11
Moonwalker Mouse
Chapter
Becker EBE., (2021), Handbook of the Cerebellum and Cerebellar Disorders: Second Edition: Volume 3, 1773 - 1788
Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology
Journal article
Argent L. et al, (2020), Journal of Biological Chemistry, 295, 12716 - 12726
Single-cell sequencing of human iPSC-derived cerebellar organoids shows recapitulation of cerebellar development
Preprint
Nayler S. et al, (2020)
Deconstructing cerebellar development cell by cell
Journal article
Van Essen M. et al, (2020), PLoS Genetics
Deconstructing cerebellar development cell by cell
Journal article
van Essen MJ. et al, (2020), PLOS Genetics, 16, e1008630 - e1008630
A gene expression signature in developing Purkinje cells predicts autism and intellectual disability co-morbidity status
Journal article
Clifford H. et al, (2019), Scientific Reports, 9
TRPC3 is a major contributor to functional heterogeneity of cerebellar Purkinje cells
Journal article
Wu B. et al, (2019), eLife, 8
Neurodegeneration in SCA14 is associated with increased PKCγ kinase activity, mislocalization and aggregation
Journal article
Wong MMK. et al, (2018), Acta Neuropathologica Communications, 6
TRPC3 is essential for functional heterogeneity of cerebellar Purkinje cells
Preprint
Wu B. et al, (2018)
The Use of Stem Cell-Derived Neurons for Understanding Development and Disease of the Cerebellum
Journal article
Nayler SP. and Becker EBE., (2018), Frontiers in Neuroscience, 12
A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem Cells
Journal article
Watson LM. et al, (2018), The Cerebellum, 17, 419 - 427
Genotype-phenotype correlations, dystonia and disease progression in spinocerebellar ataxia type 14
Journal article
Chelban V. et al, (2018), Movement Disorders, 33, 1119 - 1129
Cerebellar involvement in autism and ADHD
Chapter
Bruchhage MMK. et al, (2018), The Cerebellum: Disorders and Treatment, 61 - 72