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Correcting visual loss by genetics and prosthetics

Journal article

Xue K. and MacLaren RE., (2020), Current Opinion in Physiology, 16, 1 - 7

Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy

Journal article

Chandler L. et al, (2020), International Journal of Molecular Sciences, 21, 4972 - 4972

Cell-Mediated Inflammatory Response to AAV Gene Therapy in the Retina

Conference paper

Chandler LC. et al, (2020), MOLECULAR THERAPY, 28, 515 - 516

Highest reported visual acuity after electronic retinal implantation

Journal article

Cehajic Kapetanovic J. et al, (2020), Acta Ophthalmologica

Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR

Journal article

Cehajic-Kapetanovic J. et al, (2020), Nature Medicine, 26, 354 - 359

Association of Messenger RNA Level With Phenotype in Patients With Choroideremia

Journal article

Fry LE. et al, (2020), JAMA Ophthalmology, 138, 128 - 128

The Impact of Progressive Visual Field Constriction on Reading Ability in an Inherited Retinal Degeneration

Journal article

Jolly JK. et al, (2020), Ophthalmologica, 243, 207 - 216

Looking towards gene therapy: Characterisation of ex vivo AAV2.CYP4V2 gene therapy in human retinal explants

Conference paper

Hu M. et al, (2019), CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 47, 113 - 113

Atypical choroideremia presenting with early‐onset macular atrophy

Journal article

Kontos G. et al, (2019), Acta Ophthalmologica, 97, 633 - 636

Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues

Journal article

Chandler LC. et al, (2019), Molecular Therapy - Methods & Clinical Development, 14, 77 - 89

Photoreceptor atrophy independent of retinal hemorrhages in Terson syndrome

Conference paper

Xue K. et al, (2019), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 60

Photoreceptor-specific AAV gene replacement enhanced by the adjunctive use of hydroxychloroquine in vivo

Conference paper

Chandler LC. et al, (2019), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 60

Preliminary results in 18 patients undergoing retinal gene therapy for X-linked retinitis pigmentosa with codon-optimized AAV8-RPGR

Conference paper

MacLaren RE. et al, (2019), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 60

Vector shedding and immunology measures in a choroideremia gene therapy trial

Conference paper

Barnard AR. et al, (2019), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 60

A detailed in vivo analysis of the retinal nerve fibre layer in choroideremia

Journal article

Fu DJ. et al, (2019), Acta Ophthalmologica, 97, e589 - e600

Near-Infrared Autofluorescence in Choroideremia: Anatomic and Functional Correlations

Journal article

Birtel J. et al, (2019), American Journal of Ophthalmology, 199, 19 - 27

Non-syndromic inherited retinal disease: choroideremia

Chapter

XUE K. et al, (2019), Practical Genomics for Clinical Ophthalmology

Robot-assisted retinal surgery: overcoming human limitations

Chapter

XUE K. et al, (2019), Surgical Retina

Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia

Journal article

Xue K. et al, (2018), Nature Medicine, 24, 1507 - 1512

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