NIHR LCRN Studies
The Critical Care Research Group undertakes a number of studies that are adopted by the NIHR local research network portfolio.
GaINs: A multi-centre, UK based, genomic association study of the genetic determinants of the susceptibility to, and outcome from severe life-threatening infection and sepsis
ISOC2: The Intensive Care Study of Coagulopathy-2: A prospective cross-sectional observational study of haemostatic testing in patients admitted to adult critical care with prolongation of prothrombin time and receiving transfusions of plasma.
Measuring oxygen consumption: An assessment of the practicality of in-line gas analysis for carbon dioxide, oxygen and water vapour in the settings of cardiopulmonary exercise testing, anaesthesia and intensive care
Multi-stem cell therapy for patients with ARDS: A study to examine the safety (and potential efficacy) of the adult stem cell investigational product, MultiStem, in adults who have AcuteRespiratory Distress Syndrome (ARDS). The primary hypothesis is that MultiStem will be safe in ARDS patients.
Rescue-ASDH: Study focused on adult head injured patients who require an operation to evacuate an acute sub-dural heamatoma
REST : pRotective vEntilation with veno-venouS lung assisT in respiratory failure (The REST Trial)
SILENCE: The SILENCE Programme is a series of studies designed to lower noise levels, improve sleep hygiene, and ultimately reduce the incidence of ICU-acquired delirium.
Non-contact vital signs monitoring: A single-site study investigating the feasibility of monitoring patient vital signs in the intensive care unit.