Our goal is to define how activity in large populations of neurons is coordinated in healthy movement and how such coordination may go awry in diseases, translating this information in to improved treatment for Parkinson’s Disease and other disorders of movement.

Experimental neurology image
Regions coupled to activity in brainstem locomotor area at alpha (blue) and beta (yellow) frequencies

The Experimental Neurology Group is led by Professor Peter Brown and has made major advances in understanding how abnormal interactions between brain cells cause slowness of movement, tremor and stiffness in patients with Parkinson’s Disease.

The group takes a multidisciplinary approach combining experimental manipulations with sophisticated signals analysis and modelling. The group’s ultimate goal is to utilise their discoveries to improve treatment in Parkinson’s Disease and other illnesses where similar principles apply. 

The research programme is one of five comprising the Medical Research Council Brain Network Dynamics Unit at the University of Oxford, which Professor Brown directs.

Selected publications

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