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Study: Task-dependent modulation of phase-dependency of cortical excitability: an EEG, tACS and TMS study (in healthy volunteers)

Study Advertisement, 15th Jan 2018_v1.0
Ethics Approval Ref: R55269/RE001

Researchers at the Nuffield Department of Clinical Neurosciences, University of Oxford, are seeking volunteers for a combined Transcranial Alternating Current Stimulation (tACS)/Transcranial Magnetic Stimulation (TMS) and Electroencephalography (EEG) study.

The purpose of this study is to examine how the brain is organized, how it processes information and controls voluntary movements. We investigate this by recording EEG and then by stimulating small portions of your brain with weak electrical alternating currents (tACS) and short magnetic pulses (TMS) whilst you perform simple right hand tasks. tACS is a non-invasive tool that allows us to apply weak electrical currents through a pair of electrodes placed over the head. TMS allows us to stimulate the brain by rapid switching of a magnetic field in a coil placed over the head. Participants may experience some transient discomfort during stimulations.

Who are we looking for? Healthy men or women aged 18-60, right handed, who do not have a personal or family history of epilepsy/other neurological or psychiatric diagnosis, no heart problems, or intracranial metallic or magnetic pieces, pacemakers or other implantable medical devices. You should not be pregnant and must meet our Safety Criteria (a researcher will formally screen you using a questionnaire). This study involves two visits to the West Wing of the John Radcliffe Hospital, Oxford, that are expected to last no more than 1 hour 15 minutes and 2 hours 30 minutes, respectively. Depending on participant’s preference the two visits can also be performed on the same day. Participants will be reimbursed for their time.

If you are interested in participating in this study and/or would like further information, please contact Emma Falato, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford via email: emma.falato@ndcn.ox.ac.uk
Thank you for your time!