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White matter and myelin plasticity

Our team

© Malte Kaller (Clark et al. 2017, Brain)

WHITE matter and Myelin plasticity

 

White matter plasticity is a recently described mechanism by which experience shapes brain structure and function during adulthood. This phenomenon was first described in adult humans with complex motor skill learning using whole brain non-invasive diffusion tensor imaging (DTI). We use magnetic resonance imaging (MRI) as a translational tool in conjunction with established cellular techniques and transgenic models to elucidate the underlying cellular mechanisms of white matter plasticity.


Investigators: Heidi Johansen-Berg, Alberto Lazari, Florence Heath, Malte Kaller

Collaborators: David Bannerman (Experimental Psychology, University of Oxford), Vlad Vyazovskiy (DPAG, University of Oxford), William Richardson (UCL), Cassandra Sampaio-Baptista (University of Glasgow)

Current Funders: Wellcome Trust

Selected publications