In this research area novel methodological approaches are developed for working with extremely large databases of MR images, or images and genetics, and the complex statistics required in neuroimaging.
\n \n\n \n \nThe Pain Analgesia/Anaesthesia Imaging Neuroscience group is a multidisciplinary team of scientists and clinicians. We research how the human central nervous system generates and modulates painful experiences in acute and chronic settings.
\n \n\n \n \nOur group uses multimodal approaches to understand physiological changes in the brain, both in the context of learning novel motor skills and in a range of neurological conditions. To do this we use MR Spectroscopy, MR Imaging, Magnetoencephalography (MEG) and Non-Invasive Brain Stimulation.\r\n\r\nUltimately we hope to understand more about how the brain adapts to new challenges, so that we can develop new adjunctive therapies for recovery.
\n \n\n \n \nOur group uses computer simulations and mathematical analyses to understand the information processing and activity dynamics of brain networks underlying decision making. We use these models to investigate how neural circuits work in the healthy state, how their dynamics deteriorate in neurological disorders, and how their dynamics and information processing may be best restored by treatments.
\n \n\n \n \nResearch, diagnostic and testing service of autoantibodies associated with neurological diseases.
\n \n\n \n \nWe are a forward-looking dynamic group interested in all aspects of clinical and experimental epileptology with an emphasis on clinically relevant research. The Group draws together all relevant disciplines across Oxford University Hospitals and the University of Oxford.
\n \n\n \n \nOur aim is to understand fundamental biological processes that could inform the development of targeted therapies and innovative biomarkers in neurodegenerative and neurogenetic disorders.
\n \n\n \n \nWe use brain imaging techniques to investigate the human visual system, both in its normal state and in disease and disorder.
\n \n\n \n \nOur work focuses on translating imaging analysis methods to better understand processes such as brain maturation and ageing, with a particular emphasis on neurodegenerative disorders (Alzheimer's, Parkinson's, Huntington's, etc.), Big Data (e.g., UK Biobank) and genetics.
\n \n\n \n \nThe Critical Care Research Group undertakes a programme of research which focuses on the identification of early patient deterioration and long-term clinical outcomes of patients who have been admitted to an Intensive Care Unit (ICU). We are a team of clinicians, nurses, midwives, allied health professionals, statisticians, data scientists, and engineers, with a strong track record of supporting research careers across disciplines.
\n \n\n \n \nWe want to understand how - and why - brain function can be disturbed to lead to poor memory and loss of motivation (apathy). Our aim is to develop new treatments for these conditions across a range of neurological disorders.
\n \n\n \n \nOur aim is to gain a better understanding of the response of the peripheral nervous system to injury in order to develop strategies to promote peripheral nerve repair and to prevent the development of neuropathic pain. To do this we employ a variety of multi-disciplinary techniques ranging from transgenic models to human psychophysical studies and genetics.
\n \n\n \n \nCombining state-of-the-art brain imaging methods, we aim to understand how functional networks in the brain respond and adapt to epilepsy and epilepsy-associated lesions.
\n \n\n \n \nThe Clinical Ophthalmology Research Group is led by Professor Robert MacLaren. Over the last decade, Professor MacLaren has been at the forefront of translational medical research into novel clinical treatments for incurable retinal diseases, and is regarded internationally as a leader in the fields of retinal gene therapy, electronic retinas and ocular robotic surgery.
\n \n\n \n \nOur research focuses on light dependent signalling in the retina and brain, including visual and non-visual light detection. We are also examining novel opsin photopigments and exploring their applications to optogenetics.
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