Our research interests include cortical disorders of vision and cognitive neuroscience particularly using eye movements to understand brain function and as biomarkers for neurodegenerative diseases.
Our group has researched widely in cognitive neuroscience and visual sciences, particularly using the analysis of abnormalities of visual perception and eye movements in human neurological disease to further understanding of brain function.
Currently we are particularly interested in the cognitive control of movement using saccadic (fast conjugate) eye movements as the exemplar. In patients with neurodegenerative diseases such as Parkinson’s disease and Huntington’s disease we are studying self-initiated action, the control of action when we suddenly have to stop or change our movements and the role of short-term working memory.
We are also studying the utility of saccadic eye movements as a biomarker for the recognition of early neuronal dysfunction in pre-symptomatic patients with the genetic mutation for Huntington's disease and in patients with early Parkinson’s disease and motor neurone disease.
On a different theme we study implicit sequence learning in normal subjects and patient with hippocampal lesions using fMRI to analyse the brains areas involved.
Our research on simulating prosthetic vision has led us to try to develop a low-cost non-invasive visual prosthetic for partially sighted and blind individuals to assist them in navigating their environment.