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Basic Science

In this section
© Paula Rocktaeschel
Immunofluorescent labelling of two non-neuronal, glial cells (so-called astrocytes) generated from human stem cells to examine the impact of neuronal-glial interaction on epileptogenesis.

We maintain a strong focus on basic scientific research that can lead to therapeutic benefit.

For example, current projects include work examining the TSC2 complex of tuberous sclerosis, electrophysiological studies of surgically resected epileptogenic tissue and deregulation of NMDA receptor function in hippocampal sclerosis.

We are part of the Oxford Neurodevelopment Consortium and are keen to engage with partners interested in improved molecular understanding of what drives seizures.

Selected publications

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