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The ACORN study will identify and characterise patients and asymptomatic family members who carry the C9orf72 gene mutation, and create a national register of this cohort, facilitating further research and study participation.

Study aims

ACORN is a national research study aimed at understanding more about the genetic basis of Motor Neuron Disease (MND) and Frontotemporal Dementia (FTD).

This exciting area of research could contribute to the development of new therapeutic strategies and neurochemical biomarkers for these neurodegenerative diseases.

As a part of the study, we will create a national register of MND and FTD patients and their family members, for future research.

View the acorn study participant information sheet


For more information, or to register your interest in participating in the study - as a patient, family member or healthy volunteer - please contact the ACORN study team by email at: or by phone at: 01865 228-371 


The study is funded by the Oxford NIHR Biomedical Research Centre (Preventive Neurology - Neurodegeneration theme), and through a generous multi-year gift from the Alan Davidson Foundation to the Oxford MND Care and Research Centre.

Alan Davidson Foundation logo      NIHR BRC logo

Get involved

For information on getting involved in other general research supported by the Biomedical Research Centre at the University of Oxford, please visit their website at:  Oxford NIHR Biomedical Research Centre.


A C9orf72 HRE+ National Register and Characterisation Study ('ACORN')

Funders: Oxford NIHR Biomedical Research Centre, Alan Davidson Foundation 

Sponsor: University of Oxford

This study has been approved by:

London - Surrey Research Ethics Committee   Reference: 23/LO/0507 

Scotland A Research Ethics Committee   Reference: 23/SS/0097