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Neurodegenerative diseases such as Parkinson’s, Alzheimer’s, and Huntington’s occur as a result of the progressive loss of structure or function of neurons. SCRD is often associated with neurodegenerative disease as well as other neurological conditions such as chronic pain and stroke.

SCRD treatment is emerging as a possible approach to improve the overall health of patients, and in some conditions slow the progression of decline. For example, the impact of fragmented night-time sleep in patients with Alzheimer’s disease (AD) is very debilitating to both patients and caregivers and is a primary reason for patient institutionalisation. Preliminary studies have shown that sleep stabilisation in combination with light therapy in institutionalised patients with AD, improves night-time sleep, elevates daytime activity, decreases daytime sleep and produces a significant improvement in cognition.

We are currently developing research proposals in the areas of Huntington’s disease, Parkinson’s disease and neurosurgery, stroke and pain to:

  1. Define the nature of SCRD in neurodegenerative disease, pain and stroke.
  2. Address the causal relationships between SCRD, neurodegenerative disease, pain and stroke.
  3. Determine the appropriate next steps for the prevention and amelioration of SCRD. 

Our team

  • Kay Davies
    Kay Davies

    Dr Lee's Professor of Anatomy and Director of the MRC Functional Genomics Unit

  • Christopher Kennard
    Christopher Kennard

    Emeritus Professor

  • Irene Tracey
    Irene Tracey

    Head of Department & Nuffield Chair in Anaesthetic Science, Nuffield Department of Clinical Neurosciences, University of Oxford