CRISPR workshop
Who is this workshop for?
This workshop is for early career investigators and DPhil students at the University of Oxford.
Date and venue
Tuesday 20 June, 1.30-6.30pm, T S Eliot Lecture Theatre, Merton College
Sponsored by the NIHR Oxford Biomedical Research Centre's Gene and Cell Therapy theme
Registration
programme
| 1.30 | REGISTRATION | |
| 2.00 | Robert MacLaren, Lead of the Gene and Cell Therapy theme, NIHR Oxford Biomedical Research Centre | Welcoming address |
| 2.05 | SESSION 1: CRISPR DELIVERY SYSTEMS (Chair: Monica Hu) | |
| Jakob Haldrup Jensen, Postdoctoral Research Scientist, Radcliffe Department of Medicine | Engineered lentivirus-derived nanoparticles (LVNPs) for delivery of ribonucleoprotein complexes supporting in vivo gene disruption and prime editing | |
| Ian Hsu, DPhil Student, Radcliffe Department of Medicine | CRISPR gene-editing systems for haematopoietic stem cells | |
| Monica Hu, DPhil Student, Nuffield Department of Clinical Neurosciences | Base editing of APOE2 in the retina using a 'hit and run' lentivirus vector | |
| 2.45 | SESSION 2: PRIME EDITING (Chair: Lauren Major) | |
| Silja Hansen, Postdoctoral Research Scientist, Nuffield Department of Clinical Neurosciences | Prime editing in inherited retinal diseases | |
| Roman Doll, DPhil Student, Radcliffe Department of Medicine | Optimizing pegRNA design in HEK293T cells | |
| Lauren Major, DPhil Student, Nuffield Department of Clinical Neurosciences | Prime editing: the problem of size for in vivo delivery | |
| 3.25 | COFFEE BREAK | |
| 3.55 | SESSION 3: BASE EDITING (Chair: Elena Piotter) | |
| Weijiao Zhang, Postdoctoral Research Scientist, Wellcome Centre for Human Genetics | Development of genome editing based therapies for severe immune mediated disease | |
| Siyu Liu, DPhil Student, Radcliffe Department of Medicine | Activation of the embryonic zeta-globin expression by base editing | |
| Elena Piotter, DPhil Student, Nuffield Department of Clinical Neurosciences | Targeting a nonsense mutation in ABCA4 using DNA and RNA base editors | |
| 16.35 | SESSION 4: RNA EDITING (Chair: Sophia Bellingrath) | |
| Muhammad Hanifi, DPhil Student, Radcliffe Department of Medicine | Programmable and collateral free RNA perturbation with CRISPR/dCas13 | |
| Antonio Garcia Guerra, Postdoctoral Research Scientist, Department of Paediatrics | CRISPR Rbots: Dynamic RNA devices capable of translating sensing of microRNA-argonaute complexes into CRISPR activity | |
| Sophia Bellingrath, DPhil Student, Nuffield Department of Clinical Neurosciences | Optimising RNA editing strategies to target a nonsense mutation in the CRB1 gene | |
| 5.15 | DRINKS AND REFRESHMENTS |