- Neural Injury Group Research Group
ips-derived sensory neurons
Post doctoral research fellow
My research interests are in the fields of inherited causes of pain and the myelination of peripheral neurons.
I am using a recently developed approach to differentiate induced pluripotent stem cells (ipsc) into sensory neurons. This technique is then used to investigate genetically acquired pain disorders in culture based assays. I am also working on establishing myelinating cocultures using human ipsc-derived neurons with the aim to use these to understand the pathophysiology of demyelinating neuropathies.
Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source
Weir GA. et al, (2017), BRAIN, 140, 2570 - 2585
Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source.
Weir GA. et al, (2017), Brain, 140, 2570 - 2585
Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination.
Clark AJ. et al, (2017), Brain, 140, 898 - 913