ips-derived sensory neurons
Post doctoral research fellow
My research interests are in the fields of inherited causes of pain and the myelination of peripheral neurons.
I am using a recently developed approach to differentiate induced pluripotent stem cells (ipsc) into sensory neurons. This technique is then used to investigate genetically acquired pain disorders in culture based assays. I am also working on establishing myelinating cocultures using human ipsc-derived neurons with the aim to use these to understand the pathophysiology of demyelinating neuropathies.
Molecular and cellular correlates of human nerve regeneration: ADCYAP1/PACAP enhance nerve outgrowth
BASKOZOS G. et al, (2020), Brain
The Role of Voltage-Gated Sodium Channels in Pain Signaling
Bennett DL. et al, (2019), Physiological Reviews, 99, 1079 - 1151
Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury
Baskozos G. et al, (2019), PAIN, 160, 463 - 485
Hereditary sensory neuropathy type 1-associated deoxysphingolipids cause neurotoxicity, acute calcium handling abnormalities and mitochondrial dysfunction in vitro
Wilson ER. et al, (2018), Neurobiology of Disease, 117, 1 - 14
Functional imaging in microfluidic chambers reveals sensory neuron sensitivity is differentially regulated between neuronal regions
Clark AJ. et al, (2018), PAIN, 159, 1413 - 1425