Dr Beata Godlewska , Dept. Psychiatry
Generously funded by
Royal Society Dorothy Hodgkin Research Fellow
- Principal Investigator
- Hugh Price Fellow, Jesus College
Our reality exists in three-dimensions, and binocular vision enables us to interact with the world with precision. The goal of my research is to better understand the neural basis of binocular vision, from acquisition to perception.
My research focuses on two core questions:
(1) What are the neural mechanisms supporting binocular vision, in particular stereoscopic depth perception?
(2) What signals regulate the acquisition of binocular vision through experience?
To answer these questions, my group specializes in combining behavioural psychophysics with non-invasive imaging of brain function, in particular measures of neurochemistry using novel magnetic resonance spectroscopy techniques. These signals give us rich information about the state of the brain during vision and learning.
There are strong reasons for why this research is relevant: impaired binocular vision due to amblyopia, also known as ‘lazy eye’, is the most common visual problem in children. It can lead to a lifetime of impaired vision. If we can understand how the brain combines images from two eyes, then we can use this knowledge to help people with visual problems see better.
Betina graduated from University College London with an MSc in Neuroscience. She then obtained a DPhil degree at Oxford, during which she focused on attentional modulations on binocular vision using non-invasive MR imaging. During her postdoctoral training, she made contributions to understanding how functional paradigms and neurochemistry via MR Spectroscopy measurements can be exploited to study visual perception. In 2020, Betina was awarded a Royal Society Dorothy Hodgkin Research Fellowship to establish her own research programme at the Wellcome Centre for Integrative Neuroimaging. Her research focuses on investigating plasticity in the human binocular visual system in health and disease.
Sylvana Vilca-Melendez, Dept. Psychiatry (DPhil student, co-supervisor)
2nd year Medicine / Biomedical Sciences student at Oxford are encouraged drop Betina a line to ask about possible FHS dissertation projects in the lab. Graduate level lab rotation students are also welcome.
Kathleen Tracey, FHS student 2021/22, Wadham College
Investigating the neurochemistry of the human visual system using magnetic resonance spectroscopy
IP IB. and BRIDGE H., (2021), Brain Structure and Function
Comparison of Neurochemical and BOLD Signal Contrast Response Functions in the Human Visual Cortex
Ip IB. et al, (2019), The Journal of Neuroscience, 39, 7968 - 7975
Combined fMRI-MRS acquires simultaneous glutamate and BOLD-fMRI signals in the human brain
Ip IB. et al, (2017), NeuroImage, 155, 113 - 119
GABA and Glutamate in hMT+ Link to Individual Differences in Residual Visual Function After Occipital Stroke
Willis HE. et al, (2023), Stroke
Universal Dynamic Fitting of Magnetic Resonance Spectroscopy
Clarke WT. et al, (2023)
Investigating the human binocular visual system using multi-modal magnetic resonance imaging
Bridge H. et al, (2023), Perception, 030100662311786 - 030100662311786
Event-related functional Magnetic Resonance Spectroscopy.
Koolschijn RS. et al, (2023), Neuroimage
MRI Stereoscope: A Miniature Stereoscope for Human Neuroimaging
Ip IB. et al, (2022), eneuro, 9, ENEURO.0382 - 21.2021
Learning to see in 3D with two eyes: the role of experience, plasticity and neurochemistry
- PDF document 1.3 MB
An article on learning and binocular vision for anyone interested in biology and the brain.