DPhil Student and Mabel Churn Scholar
Caroline is the recipient of a Mabel Churn Scholarship by St Cross College, and is undertaking a DPhil in Clinical Neurosciences. Her research project focuses on the application of CRISPR/Cas9 as a novel technique in the treatment of degenerative eye diseases, particularly retinitis pigmentosa. Caroline graduated from Newcastle University with a first class honours degree in BSc Cellular and Molecular Biology in 2014 and her background is in clinical genetics.
An analysis of the Kozak consensus in retinal genes and its relevance to gene therapy.
McClements ME. et al, (2021), Mol Vis, 27, 233 - 242
CRISPR genome engineering for retinal diseases
Kantor A. et al, (2021), Progress in Molecular Biology and Translational Science
Promoter Orientation within an AAV-CRISPR Vector Affects Cas9 Expression and Gene Editing Efficiency
Fry LE. et al, (2020), The CRISPR Journal, 3, 276 - 283
Extraction of Guide RNA from a Transcript for Association with Deactivated Cas9
McClements ME. et al, (2020), MOLECULAR THERAPY, 28, 280 - 281
CRISPR Interference–Potential Application in Retinal Disease
Peddle CF. et al, (2020), International Journal of Molecular Sciences, 21, 2329 - 2329