Cassandra Sampaio Baptista
- Junior Research Fellow at Worcester College
My research focuses on functional and structural plasticity with learning and rehabilitation.
I use a combination of MR methods and histological techniques in both human and rodents.
During my Dphil I tested whether factors such as performance level or amount of practice influence brain changes at a functional, structural and neurochemical level in humans. I have also used animal models of learning in combination with MRI and histology to investigate the underlying cellular mechanisms of white-matter structural plasticity.
Recently I have developed an interest in real-time feedback fMRI in order to investigate how intentional modulation of brain activity can lead to functional brain changes and behavioural improvements and thus be applied to rehabilitation of stroke patients.
Skill acquisition increases myelination and strengthens functional connectivity in the sensorimotor circuit of the adult rat
Sampaio-Baptista C. et al, (2019)
Magnetic Resonance Techniques for Imaging White Matter.
Sampaio-Baptista C. et al, (2019), Methods Mol Biol, 1936, 397 - 407
Experience-related reductions of myelin and axon diameter in adulthood
Lazari A. et al, (2018), Journal of Neurophysiology, 120, 1772 - 1775
Structural Plasticity in Adulthood with Motor Learning and Stroke Rehabilitation
Sampaio-Baptista C. et al, (2018), Annual Review of Neuroscience, 41, 25 - 40
Increasing Lateralized Motor Activity in Younger and Older Adults using Real-time fMRI during Executed Movements
Neyedli HF. et al, (2018), Neuroscience, 378, 165 - 174