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- Oxford Subarachnoid Haemorrhage Research Group Research Group
My research focuses on characterising the cognitive effects associated with psychopharmacological substances and neuropsychiatric conditions.
My current research project involves the development of brain correlates in patients who recently had a subarachnoid haemorrhage. We are trying to improve the prediction of the occurrence of side-effects in the early days after the haemorrhage, which can help in quicker treatment of side-effects. My research methods include psychopharmacology, electro-encephalogram (EEG), transcranial doppler (TCD), and neuropsychological testing.
My previous research includes projects on characterising individual differences in the neurocognitive effects of drugs of abuse and addictive behaviours. I furthermore worked on establishing cognitive and EEG markers in the prediction of response to pharmacological treatment of depression and ADHD.
MDMA, cannabis, and cocaine produce acute dissociative symptoms.
van Heugten-Van der Kloet D. et al, (2015), Psychiatry Res, 228, 907 - 912
Psychedelic symptoms of cannabis and cocaine use as a function of trait impulsivity.
van Wel JH. et al, (2015), J Psychopharmacol, 29, 324 - 334
The acute effects of MDMA and ethanol administration on electrophysiological correlates of performance monitoring in healthy volunteers.
Spronk DB. et al, (2014), Psychopharmacology (Berl), 231, 2877 - 2888
MDMA, cannabis, and cocaine produce acute dissociative symptoms
Van Heugten-Van der Kloet D. et al, (2014), Psychiatry Research
Single doses of THC and cocaine decrease proficiency of impulse control in heavy cannabis users.
van Wel JH. et al, (2013), Br J Pharmacol, 170, 1410 - 1420