Professor of Intensive Care Medicine
- Senior Clinical Lecturer & Consultant Intensivist
My research work centres on large multicentre clinical trials and cohort studies involving patients treated in intensive care units, with an emphasis on treatments for respiratory conditions. Our research group runs our own studies, and we actively participate as co-applicants in studies run from other centres.
The research group also has a strong link with the Institute of Biomedical Engineering. We investigate ways to locate patterns in physiological variables ('vital signs') which precede and predict clinical deterioration in hospitalised patients. This work is based on thousands of recordings of patients' vital signs in Oxford and elsewhere. As hospitals evolve electronic patient records, this work is being expanded beyond vital signs to include many more electronically-recorded descriptors of a patient’s condition.
Our research group also has an interest in the patient’s journey both during a stay in intensive care, and afterwards in the hospital and in their home. Current research work is looking at the effect of environmental noise on intensive care units on sleep patterns and delirium, with an overall goal of significantly reducing the ambient noise. On a longer time scale, we also look at the long-term effects of critical illnesses on patients’ quality of life.
Acoustic source localization with microphone arrays for remote noise monitoring in an Intensive Care Unit
Müller-Trapet M. et al, (2018), Applied Acoustics, 139, 93 - 100
Risk factors for new-onset atrial fibrillation on the general adult ICU: protocol for a systematic review.
Bedford J. et al, (2018), BMJ Open, 8
Out-of-hours discharge from intensive care, in-hospital mortality and intensive care readmission rates: a systematic review and meta-analysis.
Vollam S. et al, (2018), Intensive Care Med
Critical Care Health Informatics Collaborative (CCHIC): Data, tools and methods for reproducible research: A multi-centre UK intensive care database.
Harris S. et al, (2018), Int J Med Inform, 112, 82 - 89
Might High-Frequency Oscillatory Ventilation Improve the Prognosis of More Severe Acute Respiratory Distress Syndrome? Not So Sure Reply
Meade MO. et al, (2018), AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 197, 839 - 839