Generating cerebellar organoids from pluripotent stem cells.

Becker EBE., Mayer S., Kutscher LM.

Cerebellar organoids present promising tools for the modelling of human cerebellar development and diseases. As this young field grows, robust standards and transparent reporting practices are needed to ensure the reproducibility and utility of the generated cerebellar organoid models. Here, we summarize current approaches to generate cerebellar organoids and their applications. We suggest common quality control standards and biological readouts that should be considered in this emerging area.

DOI

10.1242/dmm.052478

Type

Journal article

Publication Date

2026-01-01T00:00:00+00:00

Volume

19

Keywords

Cerebellum, Development, Disease models, Organoid, Quality control, Organoids, Humans, Cerebellum, Pluripotent Stem Cells, Animals

Permalink More information Close