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Investigating the functional mechanisms behind multiple sclerosis genetic risk variants.
I received my BSc in Biological Sciences from the University of Warwick in 2011 (Top student awards 2009, 2010, 2011), and subsequently obtained my PhD from the University of Cambridge in 2015. My doctoral studies investigated genome wide association study risk variants in multiple sclerosis, focusing on the genetic and immunological mechanisms behind a small subset of variants. (Supervisors: Revd Prof Alasdair Coles and Prof Stephen Sawcer). Aware of the prevalence of next generation sequencing (NGS) in life sciences research, I decided to gain experience in NGS at the CRUK Cambridge Institute Genomics Core Facility prior to commencing a postdoctoral position at the start of 2016 in the Fugger lab.
Bioanalyzer chips can be used interchangeably for many analyses of DNA or RNA
Davies J. et al, (2016), BioTechniques, 60
Human autoimmunity after lymphocyte depletion is caused by homeostatic T-cell proliferation
Jones JL. et al, (2013), Proceedings of the National Academy of Sciences, 110, 20200 - 20205