Autoantibodies as drivers of neuropathic pain.

Farah A., Daifallah O., Singh E., Dawes JM.

Emerging evidence, supported by clinical responses to immunotherapy and the recapitulation of sensory symptoms in passive transfer models, shows that autoantibodies (AAbs) may drive neuropathic pain. These findings highlight the importance of immune profiling to enhance diagnosis and treatment, and provide molecular insights into broader pain mechanisms in clinical contexts.

DOI

10.1016/j.molmed.2025.07.003

Type

Journal article

Publication Date

2026-02-01T00:00:00+00:00

Volume

32

Pages

101 - 104

Total pages

3

Keywords

Humans, Autoantibodies, Neuralgia, Animals

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