DPhil Student and Fight for Sight Scholar
Whilst studying towards her First Class (Hons) BSc degree in Molecular and Cellular Biology at the University of Bath, Laurel joined the MRC Protein Phosphorylation and Ubiquitylation Unit in Dundee where she undertook research into the control of gene expression.
Her keen interest in translational molecular medicine led her to join Dr Kanmin Xue, Academic Clinical Lecturer at the Nuffield Laboratory of Ophthalmology, to undertake a DPhil project investigating innate immune responses to viral infection of the retina. Both Kanmin and Laurel work integrally within Professor Robert MacLaren's research team with the aim of developing effective gene therapy for inherited retinal diseases.
Chandler LC. et al, (2019), Molecular Therapy - Methods & Clinical Development, 14, 77 - 89
Hydroxychloroquine enhances the efficacy of retinal gene therapy
Chandler LC. et al, (2018), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 59
Inesta-Vaquera F. et al, (2018), Life Science Alliance, 1, e201800092 - e201800092
Enhancement of AAV Transduction Using Anti-Malarial Drugs, Hydroxychloroquine and Chloroquine
Xue K. et al, (2018), MOLECULAR THERAPY, 26, 318 - 318
Assessment of the relationship between CHM gene expression and rate of disease progression in choroideremia
Patricio MI. et al, (2017), INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 58