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EDUCATION

BSc Biological Sciences, University of Rome "La Sapienza" (Italy)

MSc (merit) Molecular Biology, University of Rome "La Sapienza" (Italy)

DPhil Molecular and Cell Biology, University of Rome "La Sapienza" (Italy) - École Normale Supérieure de Lyon (France)

MSc Chemical Biology, Linköping University (Sweden)


Collaborators

Livia Civitelli

PhD in Developmental and Cell Biology

Research fellow in Molecular Neuroscience

synucleinopathies, gut-brain axis, seeding amplification assay, extracellular vesicles

RESEARCH INTERESTS

I am a chemical biologist with a passion for amyloid chemistry, biology of amyloid proteins and mechanisms of amyloid aggregation. 

My overarching focus is to understand the role of peripheral alpha-synuclein in the outcome of Parkinson´s disease, with a special attention to the gut-brain axis, and to investigate alpha-synuclein strains as a potential source for stratification of patients within synucleinopathies.

I am an expert in the seeding amplification assay (SAA) and I have been working on optimising the method to become more robust and reproducible. The main goal is to move this assay into clinic to be used in diagnostics as a biomarker to aid in early detection of Parkinson's diseaseas.

I am also interested in deepening the understanding of the role of extracellular vesicles (EVs) in the gut-brain axis, with particular attention to the bacterial-derived EVs, and the use of EVs for biomarker discovery.