I’m responsible for promoting translational opportunities across all areas of Oxford Neuroscience from basic science to experimental medicine. Due to my background, I work closely with the MSD Business Development Office in facilitating interactions with industry. I also organise the strategic neuroscience management committees within the University. I look after a number of our international collaborations. I am actively involved in public engagement and coordinate Brain Awareness Week activities across Oxford.

Prior to joining the University, I worked for over ten years in the pharmaceutical industry where I gained extensive experience in project and portfolio management for CNS disorders. I studied for my Ph.D. with John Hardy at St Mary’s Hospital Medical School in London and have held postdoctoral positions at Johns Hopkins University, with Roger Reeves, and the Institute of Psychiatry, with Simon Lovestone. My academic research focussed on the molecular and cellular biology of neurodegenerative diseases including Alzheimer’s disease.

Recent publications

The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists

Napier S. et al, (2011), Bioorganic & Medicinal Chemistry Letters, 21, 3163 - 3167

Localization of the cystic fibrosis transmembrane conductance regulator (Cftr) to mouse chromosome 6

Siegel D. et al, (2008), Cytogenetics and Cell Genetics, 184 - 185

The α2 chain of type 1 collagen does not map to mouse chromosome 16 but maps close to the Met proto-oncogene on mouse chromosome 6

Irving NG. et al, (2008), Cytogenetics and Cell Genetics, 121 - 122

Development of a Novel High-Throughput Assay for the Investigation of GlyT-1b Neurotransmitter Transporter Function

Allan L. et al, (2006), Combinatorial Chemistry & High Throughput Screening, 9, 9 - 14

Investigating the potential role of oestrogen receptor beta (ER Beta) in affective disorders

Irving NG. et al, (2006), JOURNAL OF AFFECTIVE DISORDERS, 91, S84 - S84

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Recent publications

The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists

Localization of the cystic fibrosis transmembrane conductance regulator (Cftr) to mouse chromosome 6

The α2 chain of type 1 collagen does not map to mouse chromosome 16 but maps close to the Met proto-oncogene on mouse chromosome 6

Development of a Novel High-Throughput Assay for the Investigation of GlyT-1b Neurotransmitter Transporter Function

Investigating the potential role of oestrogen receptor beta (ER Beta) in affective disorders

Nicholas Irving

Key publications

A mouse model for Down syndrome exhibits learning and behaviour deficits

Mouse chromosome-specific markers generated by PCR and their mapping through interspecific backcrosses

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Recent publications

The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists

Localization of the cystic fibrosis transmembrane conductance regulator (Cftr) to mouse chromosome 6

The α2 chain of type 1 collagen does not map to mouse chromosome 16 but maps close to the Met proto-oncogene on mouse chromosome 6

Development of a Novel High-Throughput Assay for the Investigation of GlyT-1b Neurotransmitter Transporter Function

Investigating the potential role of oestrogen receptor beta (ER Beta) in affective disorders