Contact information
Research groups
Nick Gatford
Postdoctoral Research Associate
Subcellular Proteomics of Parkinson's Disease
My primary research interests are in modelling psychiatric illnesses using human induced pluripotent stem cell (hiPSC)-derived neurons to provide new insight into their cause and potential treatments. I use biochemistry, proteomics, and advanced microscopy to better understand what proteins bind to and influence the mislocalisation and dysfunction of alpha-synuclein; the primary toxic agent in Parkinson's Disease, in neurons generated from Parkinson's Disease patients and healthy controls.
Recent publications
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Neuroligin-3 and Neuroligin-4X form Nanoscopic clusters and regulate growth cone organization and size
Journal article
Gatford NJF. et al, (2021), Human Molecular Genetics
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Estradiol reverses excitatory synapse loss in a cellular model of neuropsychiatric disorders
Journal article
Erli F. et al, (2020), Translational Psychiatry, 10
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Nanoscopic Clustering of Neuroligin-3 and Neuroligin-4X Regulates Growth Cone Organization and Size
Journal article
Gatford NJF. et al, (2019)
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Estradiol and the Development of the Cerebral Cortex: An Unexpected Role?
Journal article
Denley MCS. et al, (2018), Frontiers in Neuroscience, 12
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Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development
Journal article
Kathuria A. et al, (2018), Molecular Psychiatry, 23, 735 - 746