Sophia Michael
DPhil student
- Clinical Fellow
I am a clinical research fellow/ DPhil candidate, working under Professors Sarosh Irani and Arjune Sen. Within the Autoimmune Neurology group, my project involves ongoing clinical and immunological characterisation of patients with autoantibody-mediated encephalitis, with particular focus on those with LGI1 and CASPR2 autoantibodies. In parallel, I am working with the Oxford Epilepsy Research group, exploring the potential role of immunological dysfunction in a large cohort of patients with pharmacoresistant epilepsy.
Colleges
Research groups
Websites
Recent publications
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Stop testing for autoantibodies to the VGKC-complex: only request LGI1 and CASPR2
Journal article
Michael S. et al, (2020), Practical Neurology
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Distinctive binding properties of human monoclonal LGI1 autoantibodies determine pathogenic mechanisms
Journal article
Ramberger M. et al, (2020), Brain, 143, 1731 - 1745
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Cognitive, neuropsychiatric and quality-of-life sequelae in LGI1-antibody disease demonstrates fatigue as the key determinant of wellbeing
Conference paper
Binks S. et al, (2020), EUROPEAN JOURNAL OF NEUROLOGY, 27, 77 - 77
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Real-world prevalence of autoantibodies in epilepsy
Conference paper
McGinty RN. et al, (2020), EUROPEAN JOURNAL OF NEUROLOGY, 27, 61 - 61
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Intrathecal B cell activation in LGI1-antibody encephalitis
Journal article
lehmann-horn K. et al, (2019), Neurology: Neuroimmunology & Neuroinflammation.