- Clinical Fellow
I am a clinical research fellow/ DPhil candidate, working under Professors Sarosh Irani and Arjune Sen. Within the Autoimmune Neurology group, my project involves ongoing clinical and immunological characterisation of patients with autoantibody-mediated encephalitis, with particular focus on those with LGI1 and CASPR2 autoantibodies. In parallel, I am working with the Oxford Epilepsy Research group, exploring the potential role of immunological dysfunction in a large cohort of patients with pharmacoresistant epilepsy.
Stop testing for autoantibodies to the VGKC-complex: only request LGI1 and CASPR2
Michael S. et al, (2020), Practical Neurology
Distinctive binding properties of human monoclonal LGI1 autoantibodies determine pathogenic mechanisms.
Ramberger M. et al, (2020), Brain, 143, 1731 - 1745
Cognitive, neuropsychiatric and quality-of-life sequelae in LGI1-antibody disease demonstrates fatigue as the key determinant of wellbeing
Binks S. et al, (2020), EUROPEAN JOURNAL OF NEUROLOGY, 27, 77 - 77
Real-world prevalence of autoantibodies in epilepsy
McGinty RN. et al, (2020), EUROPEAN JOURNAL OF NEUROLOGY, 27, 61 - 61
Intrathecal B cell activation in LGI1-antibody encephalitis
lehmann-horn K. et al, (2019), Neurology: Neuroimmunology & Neuroinflammation.