Postdoctoral Research Scientist
Tina’s research background is focused on cellular and molecular biology of endocytic receptors of the renal proximal tubules and retinal pigment epithelium. During her PhD studies she investigated the proximal tubular function in patients and transgenic mice with cubilin and megalin dysfunction.
She later on during her postdoctoral studies applied this knowledge to study the role of these receptors in ocular physiology and pathologies through histological and ultrastructural investigations of ocular tissue from conditional transgenic mouse models.
Tina joined Professor MacLaren´s research group in 2017 and is now working in a collaborative project with OxStem Ocular to develop novel therapies for retinopathies using small molecules.
Megalin Is Predominantly Observed in Vesicular Structures in First and Third Trimester Cytotrophoblasts of the Human Placenta.
Storm T. et al, (2016), J Histochem Cytochem, 64, 769 - 784
Megalin-deficiency causes high myopia, retinal pigment epithelium-macromelanosomes and abnormal development of the ciliary body in mice.
Storm T. et al, (2014), Cell Tissue Res, 358, 99 - 107
Detailed investigations of proximal tubular function in Imerslund-Gräsbeck syndrome.
Storm T. et al, (2013), BMC Med Genet, 14
Renal phenotypic investigations of megalin-deficient patients: novel insights into tubular proteinuria and albumin filtration.
Storm T. et al, (2013), Nephrol Dial Transplant, 28, 585 - 591
Endocytic receptors in the renal proximal tubule.
Christensen EI. et al, (2012), Physiology (Bethesda), 27, 223 - 236