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We aim to understand processes of selective attention and action, learning and memory in the human brain. Through experiments in healthy volunteers and patients with brain disorders we seek to characterize how information processing networks respond (adaptively or maladaptively) when challenged by interference. Our motivation is to develop rational neurocognitive intervention strategies to help promote recovery from conditions such as depression and brain injury.
The Pain Analgesia/Anaesthesia Imaging Neuroscience group is a multidisciplinary team of scientists and clinicians. We research how the human central nervous system generates and modulates painful experiences in acute and chronic settings.
Our group uses computer simulations and mathematical analyses to understand the information processing and activity dynamics of brain networks underlying decision making. We use these models to investigate how neural circuits work in the healthy state, how their dynamics deteriorate in neurological disorders, and how their dynamics and information processing may be best restored by treatments.
Research, diagnostic and testing service of autoantibodies associated with neurological diseases.
We are developing a set of 'smart' electronic glasses (‘smart specs’) to enhance sight for the visually impaired.
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We are a forward-looking dynamic group interested in all aspects of clinical and experimental epileptology with an emphasis on clinically relevant research. The Group draws together all relevant disciplines across Oxford University Hospitals and the University of Oxford.
Our aim is to understand fundamental biological processes that could inform the development of targeted therapies and innovative biomarkers in neurodegenerative and neurogenetic disorders.
We use brain imaging techniques to investigate the human visual system, both in its normal state and in disease and disorder.
Our work focuses on translating imaging analysis methods to better understand processes such as brain maturation and ageing, and with a particular emphasis on neurodegenerative disorders (Alzheimer's, Parkinson's, Huntington's, ALS) and Big Data (UK Biobank, Lifespan HCP).
We want to understand how - and why - brain function can be disturbed to lead to poor memory and loss of motivation (apathy). Our aim is to develop new treatments for these conditions across a range of neurological disorders.
Our aim is to gain a better understanding of the response of the peripheral nervous system to injury in order to develop strategies to promote peripheral nerve repair and to prevent the development of neuropathic pain. To do this we employ a variety of multi-disciplinary techniques ranging from transgenic models to human psychophysical studies and genetics.
Combining state-of-the-art brain imaging methods, we aim to understand how functional networks in the brain respond and adapt to epilepsy and epilepsy-associated lesions.
The Clinical Ophthalmology Research Group is led by Professor Robert MacLaren. Over the last decade, Professor MacLaren has been at the forefront of translational medical research into novel clinical treatments for incurable retinal diseases, and is regarded internationally as a leader in the fields of retinal gene therapy, electronic retinas and ocular robotic surgery.