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Researchers discover how cells handle the Parkinson’s disease-causing protein alpha-synuclein
Clinical Neurology Research
15 June 2023
University of Oxford and Selvita collaborate to advance potential therapeutics for Parkinson's Disease
Clinical Neurology Research
26 May 2023
The University of Oxford and Selvita (WSE: SLV), one of the largest contract research organisations in Europe, are collaborating on drug discovery in the area of Parkinson's disease
Oxford Epilepsy Research Group Papers Highlighted
Clinical Neurology Publication Research
2 May 2023
Two papers by early career researchers in our Oxford Epilepsy Research Group have been highlighted recently.
Surgery for sciatica reduces leg pain and disability, but benefits are short-lived
Clinical Neurology Research
20 April 2023
And the certainty of evidence supporting its use is low, say researchers
European Platform for Neurodegenerative Diseases launches repository of cohorts for researchers
Clinical Neurology Research
14 March 2023
The new Cohort Catalogue will facilitate discovery of over 60 neurodegeneration research cohorts from 17 countries across Europe
Ashmolean turns red for World Encephalitis Day
Clinical Neurology
23 February 2023
Our researchers are tackling the devastating brain condition encephalitis.
Bioelectronic implant offers an intelligent therapy to treat incontinence
Clinical Neurology MRC BNDU Research
31 January 2023
The first participants in a clinical trial of a bioelectrical therapy to treat incontinence have received their 'smart' bioelectronic implants.
Direct evidence of reduced NMDA receptors in people with form of encephalitis
Clinical Neurology Research
3 January 2023
NMDAR-antibody encephalitis is an autoimmune brain condition caused by patient’s own antibodies that bind to NMDA (N-Methyl-D-Aspartate) receptors in the synapses between nerve cells.
The risk of seizures and epilepsy is higher after COVID than after the flu
Clinical Neurology Coronavirus Research
21 November 2022
New study shows clinical symptoms for Alzheimer’s can be predicted in preclinical models
Clinical Neurology Research
10 November 2022
Establishing preclinical models of Alzheimer’s that reflect in-life clinical symptoms of each individual is a critically important goal, yet so far it has not been fully realised. A new collaborative study from the University of Oxford has demonstrated that clinical vulnerability to an abnormally abundant protein in Alzheimer’s brain is in fact reflected in individual patient induced pluripotent stem cell-derived cortical neurons.
New insights gained into how the brain encodes information about the world
Clinical Neurology Research
27 September 2022
Scientists have developed a new way to test the theory that active neurons can change what they signal in the world, rather than keeping a stable correspondence to things (such as a features of an object, or ideas).
Oxford and Quinnipiac researchers discuss integrated clinical care, education, and research in multiple sclerosis
Clinical Neurology Research Teaching
21 September 2022
Mount Sinai Rehabilitation Hospital's Mandell Center for Multiple Sclerosis Care and Neuroscience Research welcomed University of Oxford partners in September. Stakeholders from University of Oxford and Quinnipiac University met to discuss ongoing research and future opportunities to develop a Mandell MS Center concept of care in the UK.
Repurposed drug could help patients with motor neuron disease
Clinical Neurology Research
11 August 2022
A drug typically used to treat enlarged prostates and high blood pressure has shown promise as a potential new therapy for motor neuron disease (MND), according to a new study.
Finding out more about Parkinson’s by monitoring symptoms at home
Clinical Neurology Research
8 August 2022
Professor Chrystalina Antoniades explains how the COVID pandemic accelerated an innovation in one research project into Parkinson's Disease.
Insights into the molecular pathways of progressive multiple sclerosis
Clinical Neurology Research
24 June 2022
Text by Ian Fyfe for 'Nature Reviews Neurology'
Discovery of gene involved in chronic pain creates new treatment target
Clinical Neurology Research
15 June 2022
Our researchers have discovered a gene that regulates pain sensitisation by amplifying pain signals within the spinal cord. This is helping them to understand an important mechanism underlying chronic pain in humans, and provides a new treatment target.
Lymph nodes reveal more about mechanisms of autoimmunity
Clinical Neurology Research
13 June 2022
Two recent papers show that studying lymph nodes reveals details of the mechanisms of autoimmunity.
Multiple heart-related conditions linked to triple dementia risk, regardless of genetics
Clinical Neurology Research
9 June 2022
Having multiple conditions that affect the heart is linked to a greater risk of dementia than having high genetic risk, according to a large-scale new study.
NDCN research presented at Myasthenia Gravis conference
Clinical Neurology Research
7 June 2022
The 14th Quinquennial Myasthenia Gravis Federation of America International Conference was recently held in Miami with 450 delegates attending in person, including over 100 from industry.
European Magnetic Resonance Imaging in MS Group celebrates 20 years
Clinical Neurology Event
20 May 2022