Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

The effects of neurotoxic and neurotrophic factors and the role of electrochemical signals were investigated using the nesting multiple electrode array chamber (MEA) model. The MEA model involves two interconnected chambers for culturing cells on top of multiple electrodes. It was observed that isolated spinal cord neuronal cells and DRGs, grown in modified Bottenstein and Sato's culture medium (BSF-2) in 5% FCS were cultured on either side of the chamber in close proximity to the grooves. The results show that both DRG and mixed neuronal cells successfully grew on coated MEAs and exhibited neurite extensions through the channels.


Conference paper

Publication Date