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Discovery of gene involved in chronic pain creates new treatment target

Clinical Neurology Research

Our researchers have discovered a gene that regulates pain sensitisation by amplifying pain signals within the spinal cord. This is helping them to understand an important mechanism underlying chronic pain in humans, and provides a new treatment target.

Lymph nodes reveal more about mechanisms of autoimmunity

Clinical Neurology Research

Two recent papers show that studying lymph nodes reveals details of the mechanisms of autoimmunity.

Multiple heart-related conditions linked to triple dementia risk, regardless of genetics

Clinical Neurology Research

Having multiple conditions that affect the heart is linked to a greater risk of dementia than having high genetic risk, according to a large-scale new study.

NDCN research presented at Myasthenia Gravis conference

Clinical Neurology Research

The 14th Quinquennial Myasthenia Gravis Federation of America International Conference was recently held in Miami with 450 delegates attending in person, including over 100 from industry.

Magnetic signatures of the brain characterised in UK Biobank imaging study

Integrative Neuroimaging Research

A study published this week in Nature Neuroscience demonstrates how studying the magnetic properties of tissue may provide a unique window into brain health and disease.

NICE recommends offering app-based treatment for people with insomnia instead of sleeping pills

Ophthalmology Research

Hundreds of thousands of people suffering from insomnia who would usually be prescribed sleeping pills could be offered an app-based treatment programme instead, NICE has said.

Developmental dynamics of the neural crest–mesenchymal axis in creating the thymic microenvironment

Clinical Neurology Research

A new paper from researchers at the Department of Paediatrics and the Nuffield Department of Clinical Neurosciences has shown that fibroblasts in the thymus, often considered simply as dull “structural” cells, are much more complex than previously thought.

How to use the science of the body clock to improve our sleep and health

Ophthalmology Public engagement Research

Professor Russell Foster has written a new book about circadian neuroscience which is published by Penguin this week. This book review by Jacqueline Pumphrey was first published on the University of Oxford website.

Funding awarded for autoimmune disease research

Clinical Neurology Research

Dr Kate Attfield awarded project funding by Connect Immune Research and The Lorna and Yuti Chernajovsky Biomedical Research Foundation.

Oxford researchers part of major UK initiative to understand chronic pain

Clinical Neurology Integrative Neuroimaging Research

Oxford pain researchers are playing a major role in a new multi-million pound research programme launched by a consortium of funders, including UKRI, Versus Arthritis, Eli Lilly and the Medical Research Foundation.

Professor Irene Tracey nominated as Vice-Chancellor of the University of Oxford

Anaesthetics Integrative Neuroimaging

Professor of Anaesthetic Neuroscience Irene Tracey, former head of the Nuffield Department of Clinical Neurosciences, has been nominated as the next Vice-Chancellor of the University of Oxford.

MRC BNDU receives a Wellcome Collaborative Award for Parkinson’s research

MRC BNDU Research

We are delighted to announce that the MRC Brain Network Dynamics Unit has received Collaborative Award funding from Wellcome for a substantial multi-year research programme designed to advance the understanding of why dopamine-producing nerve cells are especially vulnerable in Parkinson’s.

Unique study of vascular disease reaches 20th anniversary

Research Stroke & Dementia

The only project of its kind anywhere that studies patients with all types of acute vascular events - including strokes, heart attacks, aneurysms - in order to develop better diagnostic tests and treatments celebrates its 20th anniversary this month.

Little understood brain region linked to how we perceive pain

Clinical Neurology Integrative Neuroimaging Research

A new DPAG-led review paper, published in the journal Brain, has shown that a poorly understood region of the brain called the claustrum may play an important role in how we experience pain.

New Public Engagement Ambassadors

Public engagement

We're delighted to introduce our new cohort of public engagement ambassadors for 2022.

New funding awarded to study persistent pain in inflammatory arthritis

Clinical Neurology Research

The £3.9M Wellcome Collaborative Award will be used to identify the drivers of pain in people living with rheumatoid arthritis.

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