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Heterosexual transmission of HIV is the predominant transmission mode among adults world-wide, while mother-to-child transmission accounts for the majority of HIV infections in children. Factors that affect genital tract shedding of HIV virus or cell-associated provirus in women are probably important determinants of infectiveness, and hence of transmission risk during sexual contact or delivery. This review discusses the genital HIV RNA and DNA loads in relation to those in the blood and outlines some of the parameters influencing genital tract shedding of HIV.

Original publication

DOI

10.1089/apc.1999.13.695

Type

Journal article

Journal

AIDS Patient Care STDS

Publication Date

12/1999

Volume

13

Pages

695 - 701

Keywords

Adult, Cervix Mucus, Cervix Uteri, Delivery, Obstetric, Disease Transmission, Infectious, Female, HIV Infections, HIV-1, Humans, Infectious Disease Transmission, Vertical, Male, Proviruses, Risk Factors, Sexual Behavior, Vagina, Viral Load, Virus Shedding