Metabotropic glutamate receptor agonists for schizophrenia
Harrison PJ.
<jats:title>Summary</jats:title><jats:p>A drug acting at metabotropic glutamate receptors has recently been reported to be an effective antipsychotic, breaking the rule that only dopamine receptor-blocking drugs have this property. The finding complements accumulating evidence that glutamatergic abnormalities are important in the pathophysiology of schizophrenia.</jats:p>